एक्युट मायलोइड ल्युकेमिया
|बोन म्यारो एस्पिरेटय् एक्युट मायलोइड ल्युकेमिया। एरों अउर रड क्यनाच्वंगु दु।|
एक्युट मायलोइड ल्युकेमिया (AML), वा एक्युट मायलोजेनस ल्युकेमिया रक्त कोषतेगु मायलोइड लाइनया क्यान्सर ख गुकिलि असाधारण ल्युकोसाइटतेगु तीब्र विकास जुइ। थन्यागु तीब्र विकासं याना ल्युकोसाइट बोन म्यारोय् जम्मा जुइ व हेम्याटोपोयसिसय् बाधा याइ। AML is the most common acute leukemia affecting adults, and its incidence increases with age. Although AML is a relatively rare disease, accounting for approximately 1.2% of cancer deaths in the United States, its incidence is expected to increase as the population ages.
The symptoms of AML are caused by replacement of normal bone marrow with leukemic cells, which causes a drop in red blood cells, platelets, and normal white blood cells. These symptoms include fatigue, shortness of breath, easy bruising and bleeding, and increased risk of infection. Although several risk factors for AML have been identified, the specific cause of the disease remains unclear. As an acute leukemia, AML progresses rapidly and is typically fatal within weeks or months if left untreated.
AML has several subtypes; treatment and prognosis varies among subtypes. Five-year survival varies from 15–70%, and relapse rate varies from 78–33%, depending on subtype. AML is treated initially with chemotherapy aimed at inducing a remission; patients may go on to receive additional chemotherapy or a hematopoietic stem cell transplant. Recent research into the genetics of AML has developed tests that better predict how long a patient is likely to survive and whether a drug is likely to be effective.
- ↑ Jemal A, Thomas A, Murray T, Thun M (2002). "Cancer statistics, 2002". CA Cancer J Clin 52 (1): 23–47. DOI:10.3322/canjclin.52.1.23. PMID 11814064.